Impacts of the Northern Ethiopian Conflict on Malaria Elimination Programs in the Amhara region, Northwest Ethiopia: A Time-Series Analysis

Authors

  • Mastewal Worku Amhara Public Health Institute, Bahir Dar, Ethiopia,School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia
  • Abreham Amsalu Amhara Public Health Institute, Bahir Dar, Ethiopia
  • Negese Sewagegn Amhara Public Health Institute, Bahir Dar, Ethiopia
  • Damtie Lankir Amhara Public Health Institute, Bahir Dar, Ethiopia
  • Yirdaw Emru Amhara Public Health Institute, Bahir Dar, Ethiopia
  • Taye Zeru Amhara Public Health Institute, Bahir Dar, Ethiopia,School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia
  • Kassawmar Angaw Bogale School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia
  • Asrat Agalu Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
  • Belay Bezabih Amhara Public Health Institute, Bahir Dar, Ethiopia
  • Gizachew Yismaw Amhara Public Health Institute, Bahir Dar, Ethiopia

Keywords:

malaria, incidence, ITS, war, impact, Amhara Region

Abstract

Background: Malaria remains a significant public health challenge in the Amhara Region of Ethiopia. The armed Northern conflict from 2020 to 2022 significantly impacted the Amhara region, including driving internal displacement and disrupting healthcare services. This report aimed to assess the pattern of malaria epidemiology and the impact of war on elimination programs in conflict-affected zones of the Amhara Region.

Methods: Retrospective data, cross-sectional interrupted time-series analysis, and a project model were used to estimate the impact and calculate the relative level changes from 2020 to 2022. The model was validated by comparing the results with observed malaria incidence data.

Results: Although most health institutions have restored malaria services, they are still 24% below the pre-war levels, with up to 35 weeks of treatment interruptions occurring in conflict-affected areas and significant decreases in other zones. Malaria cases reported in 2021 surpassed those from 2018–2020, reaching 2020 levels, which is concerning because of continuous service interruptions. The number of confirmed cases increased across all district categories, with non-affected districts experiencing a proportionally larger increase than conflict-affected districts. Significant damage to malaria elimination supplies occurred in conflict-affected areas, especially North Shewa and South Wollo, leading to increases in cases. Ordinary least squares regression analysis further indicates a general decline in relative incidence ratios across conflict-affected districts, underscoring the impact of conflict on malaria control efforts.

Conclusions: A significant decline from pre-war levels and ongoing service disruptions in conflict-affected areas fuel malaria transmission, reactivation, and failed elimination. These calls for malaria elimination programs and vigilance surveillance systems for community screening, active case detection and effective management, and epidemiological studies to monitor the transmission dynamics.

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Published

2025-09-21

How to Cite

Lake, M., Amsalu , A., Sewagegn, N., Lankir , D., Emru , Y., Zeru , T., Angaw , K., Agalu, A., Bezabih, B., & Yismaw, G. (2025). Impacts of the Northern Ethiopian Conflict on Malaria Elimination Programs in the Amhara region, Northwest Ethiopia: A Time-Series Analysis. Ethiopian Journal of Translational Sciences, 2(2), 30–45. Retrieved from https://ejts.aphi.gov.et/index.php/ejts/article/view/21

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Articles